Nephrogenic Systemic Fibrosis: A Radiologic Perspective
نویسنده
چکیده
THE PROBLEM The first case of what ultimately would be called Nephrogenic Systemic Fibrosis (NSF) was recognized in 1997 and subsequently reported in 2000.1 Over the ensuing years a growing body of literature has elucidated the clinical picture of the disease and the extent of organ involvement. Although the exact etiology remains unknown, all NSF patients have signifi cant chronic renal impairment (stage 4 or 5) or acute renal failure. In 2006 an association was reported between intravenous gadolinium-based contrast material used for magnetic resonance (MR) imaging and subsequent development of NSF in a small group of dialysis patients in Austria, followed by a larger study from Denmark with similar findings.2,3 Since then, researchers and government regulators alike have had these contrast agents in their crosshairs.
منابع مشابه
No Association between Gadolinium-Based Contrast Agents and Development of Nephrogenic Systemic Fibrosis: a Case Study
Nephrogenic systemic fibrosis (NSF), previously known as nephrogenic fibrosing dermopathy, is an emerging systemic fibrosing disorder that develops in the setting of renal insufficiency. Nephrogenic fibrosing dermopathy (NFD) is a fibrosing condition of the skin which shows an increased number of dendritic cells, fibroblasts and thickened collagen fibers resembling scleromyxedema. It is charact...
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